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OCN Exam Content Outline Explained

Published 2026-10-31 · Facts and text checked 2026-10-16 · Questions from our OCN study guide · Reviewed by Hana N., Quality Reviewer

The 2026 OCN test content outline has six weighted areas: Care Continuum 14%, Oncology Nursing Practice 15%, Treatment Modalities 20%, Symptom Management and Supportive Care 25%, Oncologic Emergencies 16% and Psychosocial Dimensions of Care 10%. It is based on a 2020 role delineation study of adult oncology nursing practice.

Use the weights to plan your time: the two largest areas, symptom management and treatment modalities, are 45% of the test together.

I. Care Continuum (14%)

  • Health promotion and disease prevention
  • Screening and early detection
  • Navigation and coordination of care
  • Palliative care considerations
  • Advance care planning
  • Epidemiology
  • Survivorship
  • End-of-life care

Practice: The Care Continuum questions

II. Oncology Nursing Practice (15%)

  • Scientific basis (carcinogenesis, immunology, clinical trials, genomic and genetic testing)
  • Site-specific cancer considerations (pathophysiology, diagnostics, metastatic sites, staging, performance status)
  • Scope and standards of professional practice

Practice: Oncology Nursing Foundations questions

III. Treatment Modalities (20%)

  • Surgical and procedural interventions
  • Blood and marrow transplant
  • Radiation therapy
  • Systemic therapy
  • Localized therapy
  • Targeted therapies
  • Oral therapies

Practice: Surgical and Radiation Oncology questions, Systemic Therapies questions

IV. Symptom Management and Supportive Care (25%)

  • Anatomical and surgical alterations
  • Vascular access devices
  • Pharmacologic interventions
  • Complementary and integrative modalities
  • Alterations in system functioning
  • Nutrition
  • Pain management

Practice: Pain, Fatigue and GI Symptoms questions, Hematologic and Skin Toxicities questions

V. Oncologic Emergencies (16%)

  • DIC
  • SIADH
  • Sepsis
  • Tumor lysis syndrome
  • Hypersensitivity and anaphylaxis
  • Hypercalcemia
  • Cardiac tamponade
  • Spinal cord compression
  • Superior vena cava syndrome
  • Increased intracranial pressure
  • Obstructions, pneumonitis, extravasation
  • Immune-related adverse events
  • Venous thromboembolism

Practice: Oncologic Emergencies questions

VI. Psychosocial Dimensions of Care (10%)

  • Cultural, spiritual and religious diversity
  • Altered body image
  • Learning preferences and barriers
  • Social and family dynamics
  • Coping mechanisms
  • Support for patients and caregivers
  • Psychosocial distress

Source: ONCC 2026 OCN Test Content Outline (checked 2026-10-16). The outline comes from a 2020 role delineation study of adult oncology nursing practice.

Source
FactValue and source
Exam bodyOncology Nursing Certification Corporation (ONCC)ONCC: Oncology Certified Nurse (OCN) · checked 2026-10-12
Number of questions165 questions (145 scored, 20 unscored)ONCC: 2026 Test Registration Manual · checked 2026-10-23

Want the full OCN preparation?

These questions come from our OCN study guide: full-length practice tests with every answer explained, flashcards, an AI study tutor and the audiobook.