Complete digital study edition
840 Practice Questions, 12 Full-Length ACS Organic Chemistry Exams
840 Practice Questions Across 12 Full-Length Tests, Detailed Answer Explanations and Full Content Review
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- 12 full-length practice tests, 840 questions total
- Every answer explained to teach the logic, not just the correct choice
- Top 300 must-know reactions and mechanisms for rapid review
- 6-week structured study plan that fits a packed semester
The ACS Organic Chemistry exam at a glance
- What does the ACS Organic Chemistry exam cover?
- The ACS Organic Chemistry is organized into 12 content areas: Structure: Shape and Stability; Structure: Nomenclature and Functional Groups; Structure: Constitutional, Stereochemical & Conformational Isomers; Acids and Bases; Nucleophilic Substitution Reactions; Elimination Reactions; Addition Reactions to Alkenes and Alkynes; Addition Reactions to Alcohols and Ethers; Spectroscopy; Radical Reactions; Conjugated Systems and Aromaticity; Aromatic Reactions.
- How many questions are on the ACS Organic Chemistry?
- 70 questions, with a time limit of 110 minutes.
- How should I prepare for the ACS Organic Chemistry?
- Study one content area at a time, practice with exam-style questions and read every explanation, then take full-length timed practice tests. A free readiness test is available at https://prepmasterdigital.com/readiness/acs-organic-chemistry-study-guide.
Two kinds of students face the ACS Organic Chemistry Exam: the overwhelmed and the prepared.
This guide is engineered to move you into the second camp. It delivers a semester's worth of organic chemistry distilled into high-yield review chapters, then backs them with 12 full-length practice tests totaling 840 questions, each with detailed explanations that teach logic, not just answers.
The ACS Organic Chemistry Exam Is a Different Beast
You've survived a semester of reactions, mechanisms, and multistep syntheses. But the ACS Organic Chemistry Exam doesn't ask you to recite facts; it forces you to apply them under time pressure. A typical lecture exam might give you 30 questions and 50 minutes. This one gives you 70 questions in 110 minutes, covering everything from nomenclature to spectroscopy to complex carbonyl chemistry.
Most prep materials are either too thin, with a few practice tests and no real review, or too dense, rehashing your textbook chapter by chapter. You don't need another textbook. You need a system that identifies what you actually remember, drills the high-yield topics, and builds the stamina to think clearly for two straight hours.
Your grade on this exam can influence your course grade, your GPA, and even your grad school applications. The stakes are real, but so is the solution: a focused review that mirrors the real exam's format and difficulty, with explanations that teach you why the wrong answers are wrong.
Why This Guide Is Different: It’s a Complete System, Not Just a Book
We built this guide around a single principle: you learn by doing, and you improve by understanding your mistakes. That's why it includes 12 full-length practice tests with 840 questions in the real exam's format and difficulty. Each question comes with a detailed explanation that walks you through the reasoning, not just the answer. You'll see why the correct choice is right and, just as importantly, why the other three are wrong.
But practice alone isn't enough. The guide opens with a detailed content review that covers every domain on the exam: structure and isomerism, reaction mechanisms, spectroscopy, aromatic and carbonyl chemistry, and multistep synthesis. It's written at the right level, assuming you've already had the course, so it's a refresher, not a textbook.
To keep you on track, we include a 6-week study plan that tells you exactly what to review and which practice tests to take each week. And for those last-minute moments, the Top 300 list of must-know reactions and mechanisms is your go-to cheat sheet. This is the difference between hoping you know the material and knowing you do.
Your Path to Mastery in 4 Simple Steps
- 1Take the first practice test to diagnose your weak areas.
- 2Study the focused content review, targeting the domains where you lost the most points.
- 3Take the next practice test, then review every explanation, noting your recurring mistakes.
- 4Use the Top 300 list and Digital flashcards for last-minute review, then take the final practice tests to build stamina.
Everything you get
One purchase, everything below — no subscriptions, no upsells, no extra fees. Here is exactly what unlocks the moment you buy, and how each part helps you.
840
practice questions — every answer explained
975
digital flashcards, ready to drill
~20.9h
of professional audio narration
12
downloadable study tools
Complete audiobook — about 20.9 hours
The entire book, professionally narrated. Stream it in your browser or download the MP3s and study on the commute, at the gym, or on a break — so the material sinks in even when you can't sit down to read.
AI Study Tutor — ask this book anything
A tutor that has read this exact book: ask about any topic, get an answer grounded in its own chapters, right on your access page. 5 questions are included free with your purchase, and the tutor upgrade gives you unlimited questions (fair use: 100 a day — write to us and we lift it).
ACS Organic Chemistry Reaction and Checklist
A visual guide to all key reactions and mechanisms, plus a checklist to track your mastery.
6-Week Structured Study Plan and Tracker
A day-by-day plan to pace your prep and log your progress across practice tests.
Top 300 Reagents and Mechanisms Decoder
A quick-reference decoder for the most-tested reagents, mechanisms, and functional group transformations.
Spectroscopy Cheat Sheet and Decoder
Decode IR, NMR, and mass spec data fast with this at-a-glance reference.
Multistep Synthesis Strategy Playbook
Step-by-step tactics for tackling complex synthesis problems, from retrosynthesis to execution.
ACS Exam Day Readiness Checklist
A final checklist to ensure you have everything in order for test day, from ID to pacing strategy.
Functional Group Quick Reference Card
A pocket-sized guide to all functional groups, their properties, and common reactions.
Named Reactions and Their Mechanisms Scriptbook
A scripted walkthrough of the most important named reactions, with step-by-step mechanisms.
Acid-Base Strength Ranking Worksheet
A fill-in worksheet to practice ranking acids and bases by pKa and structural factors.
Practice Test Analysis and Error Log
A structured log to analyze each practice test, categorize mistakes, and plan targeted review.
Organic Chemistry Vocabulary and Definitions Glossary
A comprehensive glossary of key terms and definitions, perfect for quick review.
Stereochemistry and Isomerism Decoder
A decoder for understanding and constitutional, stereochemical and conformational isomers with ease.
Delivered as a PDF and EPUB you can read on any device, plus downloadable audio and toolkit files. Nothing to install, and your access never expires.
Everything you'll master, chapter by chapter
The complete syllabus of this guide — built on the official exam outline.
Chapter 1: Your Study Roadmap for the ACS Organic Chemistry Exam
- ▸ Exam Blueprint, 70 Questions, 110 Minutes, and the Institute's Published Scope
- ▸ Six-Week Study Arc, Content Review, Timed Drills, and Error Analysis
- ▸ Active Recall and Spaced Repetition, Tools for Long-Term Retention
- ▸ Pacing on Test Day, Budgeting Time Across Discrete and Synthesis Questions
Chapter 2: Molecular Architecture, Shape, Stability, Nomenclature, and Functional Groups
- ▸ Hybridization and VSEPR, Predicting Geometry from Lewis Structures
- ▸ Resonance, Electron Delocalization, and Molecular Stability
- ▸ Ring Strain, Angle Strain, and Steric Strain in Cyclic Systems
- ▸ IUPAC Nomenclature, Parent Selection, Numbering, and Substituent Order
- ▸ Functional Group Families and the Reactions They Foreshadow
Chapter 3: Constitutional, Stereochemical, and Conformational Isomerism
- ▸ Classifying Isomers, Constitutional, Configurational, and Conformational
- ▸ Assigning R and S, Cahn-Ingold-Prelog Rules and Drawing Conventions
- ▸ Enantiomers, Diastereomers, and Meso Compounds, Polarity and Optical Activity
- ▸ Conformational Analysis of Alkanes and Cyclohexanes, Axial versus Equatorial
Chapter 4: Acids and Bases, Structure, Equilibrium, and Mechanistic Role
- ▸ Four Acid-Base Definitions and Their Organic Chemistry Uses
- ▸ Using pKa Values to Predict Equilibrium Direction and Product Stability
- ▸ Structural Factors That Control Acidity, Element, Hybridization, Resonance, Induction, and Solvation
- ▸ Applying Acid-Base Logic to Mechanism Selection and Reagent Choice
Chapter 5: Substitution versus Elimination, Mechanisms, Competition, and Product Prediction
- ▸ The SN2 Mechanism, Backside Attack, Steric Hindrance, and Inversion
- ▸ The SN1 Mechanism, Carbocation Stability, Leaving Group Ability, and Solvolysis
- ▸ The E2 Mechanism, Antiperiplanar Geometry and Zaitsev versus Hofmann Products
- ▸ E1 and E1cb Pathways, When Elimination Occurs without Strong Base
- ▸ Deciding between SN1, SN2, E1, and E2, A Structured Checklist
Chapter 6: Addition Reactions Across Alkenes, Alkynes, Alcohols, and Ethers
- ▸ Markovnikov Additions to Alkenes, HX, Hydration, and Rearrangement Risks
- ▸ Anti-Markovnikov Additions, Hydroboration-Oxidation and Related Stereochemical Outcomes
- ▸ Stereospecific Additions, Halogenation, Epoxidation, and Dihydroxylation
- ▸ Addition Reactions of Alkynes, Hydration, Halogenation, and Selective Reduction
- ▸ Alcohols and Ethers in Addition Chemistry, Alkoxymercuration, Epoxide Opening, and Ether Cleavage
Chapter 7: Spectroscopy, Structure Elucidation from Mass, Infrared, and NMR Data
- ▸ Mass Spectrometry, Molecular Ion, Fragmentation Patterns, and Isotope Clusters
- ▸ Infrared Spectroscopy, Identifying Functional Groups by Characteristic Absorptions
- ▸ Proton NMR, Chemical Shift, Integration, Multiplicity, and Exchange Effects
- ▸ Carbon NMR and Two-Dimensional Correlation Methods
- ▸ Integrated Structure Determination, A Step-by-Step Spectral Workflow
Chapter 8: Radical Reactions, Stability, Selective Halogenation, and Synthetic Applications
- ▸ Radical Structure, Stability, and the Three Stages of a Radical Reaction
- ▸ Alkane Halogenation, Reactivity-Selectivity Tradeoff and Radical Inhibitors
- ▸ Allylic and Benzylic Bromination with N-Bromosuccinimide
- ▸ Radical Additions and Polymerization, Anti-Markovnikov HBr and Polyethylene
Chapter 9: Conjugated Systems and Aromaticity, Electronic Structure and Cycloadditions
- ▸ Conjugation, Resonance Stabilization, and the Thermodynamics of Dienes
- ▸ Molecular Orbitals of Conjugated Pi Systems, Bonding, Nonbonding, and Antibonding
- ▸ The Diels-Alder Reaction, Diene, Dienophile, and Stereochemical Outcomes
- ▸ Aromaticity Criteria, Huckel's Rule, Annulenes, Ions, and Heterocycles
- ▸ Antiaromatic and Nonaromatic Compounds, Distinguishing by Structure and Stability
Chapter 10: Aromatic Substitution, Electrophilic Pathways, Directing Effects, and Synthesis Design
- ▸ Electrophilic Aromatic Substitution Mechanism, Sigma Complexes and Catalysis
- ▸ Activating and Deactivating Substituents, Inductive and Resonance Effects
- ▸ Ortho, Para, and Meta Directing Rules, Predicting Product Mixtures
- ▸ Common EAS Reactions, Halogenation, Nitration, Sulfonation, and Friedel-Crafts Alkylation and Acylation
- ▸ Nucleophilic Aromatic Substitution and Multistep Aromatic Synthesis Planning
Chapter 11: Carbonyl Chemistry, Aldehydes, Ketones, Carboxylic Acids, and Derivatives
- ▸ Carbonyl Electrophilicity, Structure, Polarity, and the Addition Mechanism
- ▸ Additions to Aldehydes and Ketones, Alcohols, Hydride, and Grignard Reagents
- ▸ Acetals, Imines, and Related Condensation Products, Formation and Hydrolysis
- ▸ Carboxylic Acids and Derivatives, Acidity, Acyl Substitution, and Reactivity Order
- ▸ Oxidation and Reduction across the Carbonyl Family, Choosing Reagents
Chapter 12: Enols, Enolates, and Conjugate Additions, Alpha-Carbon Reactivity
- ▸ Keto-Enol Tautomerism and the Factors That Stabilize Each Form
- ▸ Enolate Formation and Alpha-Alkylation, Base Choice and Regiochemistry
- ▸ Aldol and Crossed Aldol Reactions, Stereocontrol and Synthetic Strategy
- ▸ Claisen Condensation and Beta-Dicarbonyl Chemistry
- ▸ Michael Addition and the Robinson Annulation, Conjugate versus Direct Addition
Chapter 13: Multistep Synthesis and Applications, Retrosynthesis, Reagent Strategy, and Real-World Connections
- ▸ Retrosynthetic Analysis, Disconnections, Synthons, and Target Planning
- ▸ Functional Group Interconversion and Protecting Group Logic
- ▸ Reagent Toolkits for Carbon-Carbon Bond Formation and Chain Elongation
- ▸ Organic Chemistry in Biological Systems, Metabolic Building Blocks and Drug Design
- ▸ Organic Chemistry in Industry, Polymers, Materials, and Sustainable Processes
…plus the full-length practice exams with every answer explained.
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Common questions
How many practice tests and questions are included?
The guide includes 12 full-length practice tests, each with 70 questions, for a total of 840 questions. Every question has a detailed explanation.
Is this book aligned with the current ACS Organic Chemistry Exam format?
Yes. The practice tests are written to match the real exam's format and difficulty, covering the same topics and question types you'll encounter.
Do I get digital access to the Digital flashcards and audiobook?
Yes. Your purchase includes access to 500 digital flashcards, an audiobook version of the content review, and other digital tools. Details are inside the book.
Can I use this guide alongside my textbook and lecture notes?
Absolutely. This guide is designed to complement your course materials. It condenses the key concepts and provides extensive practice, so you can focus on what matters most.
What if I'm not satisfied with the book?
We offer a 30-day money-back guarantee. If you're not satisfied for any reason, you can return it for a full refund, no questions asked.
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